Thrombate III

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Thrombate III, Antithrombin III (Human), is indicated for the treatment of patients with hereditary antithrombin (AT) deficiency in connection with surgical or obstetrical procedures or when they suffer from thromboembolism.1

Necessary: The Only FDA-Approved Treatment for Hereditary AT Deficiency

Efficacious. Thrombate III is a potent hemostatic agent that restores the balance in hemostasis for patients with hereditary antithrombin deficiency in high-risk situations.
  Thrombate III reduces the risk of thrombotic events without increasing the risk of bleeding

Predictable. Thrombate III is highly purified antithrombin concentrate that gives physicians precise control over antithrombin levels.
  Thrombate III is purified to remove other coagulation proteins

Safe. Thrombate III has a well-established safety profile.
  Thrombate III has more than 15 years of post-marketing experience
  More than 100 million IUs have been administered with no reported case of virus transmission
  Thrombate III is pasteurized to inactivate viruses and is purified to remove proinflammatory antibodies and cytokines
  Thrombate III has a low incidence of side effects.1 The most common include dizziness, chest tightness, nausea, and a foul taste in the mouth


Reference:
1.   Thrombate III [prescribing information]. Research Triangle Park, NC; Talecris Biotherapeutics, Inc.; 2006.



Important Safety Information
Thrombate III therapy has demonstrated a low occurrence of side effects. In clinical studies with Thrombate III, the most common side effects were dizziness, chest tightness, nausea, and a foul taste in the mouth. As with all plasma-derived therapeutics, the potential to transmit infectious agents, such as viruses, cannot be totally eliminated. Individuals who receive infusions of blood or blood plasma may develop signs and/or symptoms of some viral infections, particularly hepatitis C.

Please see full Prescribing Information for Thrombate III.


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