- Antithrombin (AT) concentrate purified from human plasma
- Half-life (3.8 days) similar to endogenous AT
Pasteurized to inactivate viruses, with no confirmed cases of virus transmission
- Because THROMBATE III is made from human blood, it may carry a risk of transmitting infectious agents, eg, viruses, the variant Creutzfeldt-Jakob disease (vCJD) agent, and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent. There is also the possibility that unknown infectious agents may be present in the product.
- No known contraindications
In clinical studies, the most common adverse reactions (≥ 5% of subjects) were dizziness, chest discomfort, nausea, dysgeusia, and pain (cramps).